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Jean-Claude Martinou Selected Research

Type 2A Charcot-Marie-Tooth disease

5/2011Bioenergetic defect associated with mKATP channel opening in a mouse model carrying a mitofusin 2 mutation.
5/2010Expression of mitofusin 2(R94Q) in a transgenic mouse leads to Charcot-Marie-Tooth neuropathy type 2A.

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Jean-Claude Martinou Research Topics

Disease

8Neoplasms (Cancer)
01/2019 - 04/2004
4Mitochondrial Diseases (Mitochondrial Disease)
09/2021 - 09/2008
2Hypoxia (Hypoxemia)
10/2019 - 04/2009
2Carcinoma (Carcinomatosis)
04/2014 - 07/2005
2Type 2A Charcot-Marie-Tooth disease
05/2011 - 05/2010
1Seizures (Absence Seizure)
01/2022
1Reperfusion Injury
10/2019
1Glioblastoma (Glioblastoma Multiforme)
10/2017
1Lactic Acidosis
01/2016
1Optic Atrophy
12/2014
1Spastic Ataxia
12/2014
1Colonic Neoplasms (Colon Cancer)
05/2012
1Peripheral Nervous System Diseases (PNS Diseases)
05/2011
1Neurodegenerative Diseases (Neurodegenerative Disease)
12/2009
1Autosomal Dominant Optic Atrophy (Dominant Optic Atrophy)
06/2009
1Paralysis (Palsy)
12/2003
1Chlamydia Infections
01/2002

Drug/Important Bio-Agent (IBA)

5Proteins (Proteins, Gene)FDA Link
06/2017 - 04/2004
2RNA (Ribonucleic Acid)IBA
09/2021 - 03/2013
2Adenosine Triphosphate (ATP)IBA
08/2015 - 09/2008
2Peptide Hydrolases (Proteases)FDA Link
04/2014 - 12/2009
1CalciumIBA
01/2022
1Ketone BodiesIBA
01/2022
1gamma-Aminobutyric Acid (GABA)IBA
01/2022
1safingol (sphinganine)IBA
10/2019
1Chaperonin Containing TCP-1IBA
10/2019
1spisulosineIBA
10/2019
1Alanine (L-Alanine)FDA Link
10/2019
1SphingolipidsIBA
10/2019
1Serine (L-Serine)FDA Link
10/2019
1Oxygen (Dioxygen)IBA
10/2019
1PiperazineIBA
01/2019
1Glutamine (L-Glutamine)FDA Link
10/2017
1Mitochondrial RNAIBA
06/2017
1Translationally-Controlled 1 Tumor ProteinIBA
01/2016
1Neurotransmitter Agents (Neurotransmitter)IBA
01/2016
1Polynucleotide Adenylyltransferase (Polymerase, Poly A)IBA
12/2014
1Cisplatin (Platino)FDA LinkGeneric
04/2014
1MutagensIBA
04/2014
1Peptides (Polypeptides)IBA
04/2014
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
03/2013
1TNF-Related Apoptosis-Inducing LigandIBA
03/2013
1Death Domain ReceptorsIBA
05/2012
1Drug CombinationsIBA
05/2012
1Choline KinaseIBA
05/2012
1DNA (Deoxyribonucleic Acid)IBA
05/2012
1Membrane Proteins (Integral Membrane Proteins)IBA
05/2011
1m-AAA proteasesIBA
12/2009
1GTP Phosphohydrolases (GTPases)IBA
06/2009
1Dynamins (Dynamin)IBA
06/2009
1CeramidesIBA
04/2009
1dihydroceramide desaturaseIBA
04/2009
1StaurosporineIBA
07/2005
1Etoposide (VP 16)FDA LinkGeneric
07/2005
1Cyclosporine (Ciclosporin)FDA LinkGeneric
07/2005
1Mitochondrial Permeability Transition PoreIBA
07/2005
1titanium silicide (TS-1)IBA
12/2003
1CaspasesIBA
01/2002

Therapy/Procedure

2Therapeutics
03/2013 - 05/2012
1Ketogenic Diet
01/2022